Maternal and neonatal blood gases in prolonged labour

This study included 60 women at term. The cases were divided into two subgroups. Control group: includes 30 women with normal labour patterns, [15 cases with normal vaginal delivery and 15 cases with elective caesarean section]. Prolonged labour group; includes 30 women with abnormal prolonged labour duration [above 18 hours], [15 cases were delivered vaginally and 15 cases by caesarean section].For each patient clinical and pelvic examinations were done. Fetal and maternal blood gases were estimated.It was apparent that the maternal and the neonatal acid-base balance shifted towards acidosis in vaginal as well as in caesarean section prolonged labour cases. When comparison was done between prolonged labour cases and normal cases, the differences were statistically significant in both the vaginal and caesarean section deliveries. In prolonged labour cases, the acid-base and electrolyte balance will be disturbed and acidosis will be more pronounced

Correlation between serum procollagen-IC end terminal peptide [PCICP] levels and bone mineral density measurements in hormone treated and untreated postmenopausal women

This study aimed to compare bone mineral density measurements [BMD] and serum procollagen-1C end terminal peptide [PC1CP] level in untreated and hormone treated postmenopausal women. A cross-sectional study compared the biophysical BMD and biochemical PC1CP parameters in a group of untreated postmenopausal women [n = 50] with a group of postmenopausal women on hormone replacement therapy [HRT] [n = 35]. The results showed that the untreated postmenopausal women had higher osteoblastic and osteoclastic activity than postmenopausal women on HRT. PC1CP was 11.3% lower in the women on HRT compared with controls. The difference in bone density of L2-L4 between the two groups was 16.1%. So, it was concluded that postmenopausal women receiving HRT readjusted their bone remodeling so that although osteoblastic function was reduced, there was much greater deduction in osteoclastic function which resulted in an overall higher bone mass observed in the BMD of women on HRT